三种秦巴特色中药材的历史沿革与研究进展

赵晔; 郝晗; 耿欣; 贾梦辛; 张新新; 王美; 杨洋; 李扬; 王四旺; 郑晓晖

doi:10.16152/j.cnki.xdxbzr.2024-05-002

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三种秦巴特色中药材的历史沿革与研究进展

西北大学生物学科办学100周年专刊 | 更新时间：2024-09-30

- 三种秦巴特色中药材的历史沿革与研究进展
- The historical evolution and research progresses of three Qinba characteristic Chinese medicinal materials
- 西北大学学报（自然科学版） 2024年54卷第5期页码：767-784
- 作者机构：
  
  1.西北大学　国家中医药管理局中药化学〔三级〕科研实验室，陕西　西安　710069
  2.西安交通大学　医学部药学院，陕西　西安　710061
  3.陕西师范大学　生命科学学院，陕西　西安　710119
  4.西北大学　陕西省生物医药重点实验室，陕西　西安　710069
  5.西北大学　陕西省创新药物研究中心，陕西　西安　710069
- 作者简介：
  
  赵晔，女，博士，教授，从事中药药物化学成分分析和中药药理研究，zhaoye@nwu.edu.cn。
  郑晓晖，男，博士，教授，博士生导师，从事药物代谢、分析及应答、生物色谱分析、创新药物研究，zhengxh318@nwu.edu.cn。
- 基金信息：
  
  国家自然科学基金(81202503);陕西省重点研发计划项目(2017ZDXM-SF-017);陕西省重点科技创新团队(2016KCT-24);陕西省中医药“双链融合”中青年科研创新团队项目(2022-SLRH-YQ-002);陕西中医药传承创新暨“秦药”开发重点科学研究项目(2021-03-22-004);陕西省中管局委托科研项目(ZYJWT-2024-001)
- DOI：10.16152/j.cnki.xdxbzr.2024-05-002
  中图分类号： R28
- 纸质出版日期：2024-10-25，
  
  收稿日期：2024-08-01，
- 稿件说明：
移动端阅览
赵晔, 郝晗, 耿欣, 等. 三种秦巴特色中药材的历史沿革与研究进展[J]. 西北大学学报（自然科学版）, 2024,54(5):767-784.

ZHAO Ye, HAO Han, GENG Xin, et al. The historical evolution and research progresses of three Qinba characteristic Chinese medicinal materials[J]. Journal of Northwest University (Natural Science Edition), 2024,54(5):767-784.
赵晔, 郝晗, 耿欣, 等. 三种秦巴特色中药材的历史沿革与研究进展[J]. 西北大学学报（自然科学版）, 2024,54(5):767-784. DOI： 10.16152/j.cnki.xdxbzr.2024-05-002.

ZHAO Ye, HAO Han, GENG Xin, et al. The historical evolution and research progresses of three Qinba characteristic Chinese medicinal materials[J]. Journal of Northwest University (Natural Science Edition), 2024,54(5):767-784. DOI： 10.16152/j.cnki.xdxbzr.2024-05-002.

摘要

秦巴地区特有的气候与水土环境使陕西成为中国生物多样性最丰富的省份之一。陕西自古就是重要的中药材适生区，有“天然药库”“秦地无闲草”等美誉，道地中药材有杜仲、秦艽、丹参和黄姜等。道地性的内核是自然环境与生态条件共同演化造就了中药材的性质与功效，为了从千年临床用药经验和研究中全面认识秦巴特色中药材，本研究通过古籍资料考证结合现代研究，选取不同种属3种秦巴特色中药材杜仲、秦艽和黄姜对采收加工、性味归经、炮制提取、化学成分、功效主治、新药研发进行了梳理归纳，探析道地性的物质基础，科学阐释其作用机制，为合理利用、科学开发秦巴特色中药材提供思路，为创新中国药的现代化研发提供源泉。

Abstract

The climate

water and soil environment of Qinba has made Shaanxi one of the provinces with the richest biodiversity in China. Shaanxi has been an important area for the growth of traditional Chinese medicine since ancient times

with reputations such as "natural medicine bank" and "no idle grass in Qin land". Authentic traditional Chinese medicine includes

Eucommiae cortex

Gentianae macrophyllae radix

Salviae miltiorrhizae radix et rhizoma

and

Dioscorea zingiberensis radix et rhizoma

. The core of authenticity lies in the co evolution of natural environment and ecological conditions

which have shaped the properties and efficacy of traditional Chinese medicinal materials. In order to comprehensively understand the unique Chinese medicinal materials of Qinba from thousands of years of clinical experiences and research

this article selects three representative Chinese medicinal materials of Qinba from different genera

studies ancient books and modern research

and summarizes their harvesting and preparing

properties and flavors

processing and extraction

chemical composition

efficacy and treatment

and new drug development. It deeply explores the material basis of authentic Chinese medicinal materials

scientifically explains the mechanism of action

provides ideas for the rational use and scientific development of Qinba unique Chinese medicinal materials

and provides a source for the modern research and development of innovative Chinese medicine.

关键词

杜仲秦艽黄姜道地性秦巴特色中药材创新中国药

Keywords

Eucommiae cortexGentianae macrophyllae radixDioscorea zingiberensis radix et rhizomaauthenticityunique Chinese medicinal materials of Qinbainnovative Chinese medicine

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